MSCA Project

Neuroelectronics Interfaces Group

BioKIN

Mesh electronics for next generation skin tissue engineering

About

BIOKIN is a Marie Skłodowska-Curie Action (MSCA) project at Forschungszentrum Jülich and RWTH in Aachen, Germany.


BioKIN aims to develop a biomimetic platform for real-time monitoring of lab-grown dermo-epidermal skin substitutes.

The project will engineer an advanced hybrid skin model to enhance understanding of epidermal skin biology, skin tissue formation and skin diseases.

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Sphere Logo Illustration

BioKIN

Background


Every year, more than 11 million people around the world experience ​severe skin injuries that require treatment to help their skin heal. Among ​the various skin replacement therapies available, bioengineered skin ​stands out as the most advanced and is now the go-to solution in many ​clinics.


The popularity of bioengineered skin has also surged in the industry, ​especially after the EU banned animal testing for dermo-cosmetic ​products. This type of skin model is also valuable for research, providing ​a reliable way to study human skin without needing to test on animals.


Despite the significant advances in bioengineered skin models in the ​clinic, as well as within industry, and academic research, in situ, non-​invasive, and real-time monitoring of their performance has not been ​sufficiently addressed.


BioKIN will address this critical challenge by developing seamless devices ​to interface with bioengineered skin. By establishing an in vitro biomimetic ​platform, BioKIN will enable remote and non-destructive real-time ​monitoring of laboratory-grown skin, paving the way for the development ​of advanced living-like bionic skin substitutes.

Every year, 11 million people worldwide suffer from ​severe skin burns

Objectives

Design, fabrication, characterization and ​optimization of mesh electronics devices

Objective 1​

SPR chip

Work Package 1​

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Bioengineering and characterization of 3D ​hybrid skin cultures

Objective 2

cell culture at the cell culture laboratory

Work Package 2

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Validation: in vitro, wireless and real time ​monitoring of wound healing in the hybrid ​skin model

Objective 3

Oscilloscope

Work Package 3

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Scientists in a Laboratory

the Te​am

Prof. Dr. Ing. Francesca Santoro

Supervisor and Leader of NEI Group

Dr. Ing. Dahiana Mojena Medina

Marie Skłodowska-Curie Postdoctoral Fellow

Forschungszentrum Jülich IBI 3

Host Organization

NEI Research Group

Working surronded by Science

IBI-3 FZJ

RWTH

The "Neuroelectronic Interfaces" (NEI) Group is ​a Joint Lab between FZJ-IBI3 with the Faculty of ​Electrical Engineering and IT, RWTH Aachen.

The Group is working on Neuroengineering, ​neuromorphic biohybrids and, within the ERC ​project BRAIN-ACT, on next generation of ​interactive biohybrid platforms.


Outcomes

Events

Stay tuned for updates on ​BioKIN outreach events

online and on site

Publications

The main research outputs and ​deliverables will be managed ​according to the FAIR principles.

findable, accessible, interoperable ​and reusable

Collaborations

BioKIN is working with ME3T to ​advance biofabrication tools for ​studying epithelial mechanobiology.

Collaborate to innovate

Contact us

Forschungszentrum Jülich GmbH

Wilhelm-Johnen-Straße

52428 Jülich

Institute of Biological Information ​Processing

Bioelectronics (IBI-3)

Building 02.4v / Room 226

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Sphere Logo Illustration

BioKIN

wHERE skin Melts ​technology

Supporting excellence in research and innovation


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Funded by The european union

Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union or the ​European Research Executive Agency (REA). Neither the European Union nor the granting authority can be held responsible for ​them.

Copyright © 2024 BIOKIN

Created and Managed by D. Mojena Medina